![]() International Forum of Allergy & Rhinology published by Wiley Periodicals LLC on behalf of American Academy of Otolaryngic Allergy and American Rhinologic Society. You can use Rhinos demo version to view Rhino files and other supported file formats. Once the free trial expires, plugins will stop working unless you purchase a license. One serious procedure-related adverse event of anxiety/panic attack was reported.Ĭryotherapy is superior to a sham procedure for improving chronic rhinitis symptoms and patient quality of life.Ĭhronic rhinitis controlled trial cryotherapy quality of life randomized sham-control. Rhino offers a 90-day free trial with full access to the Rhino software. There were greater improvements in the rTNSS, RQLQ(S), and NOSE scores for the active arm over the sham arm at the 90-day follow-up (p < 0.001). The treatment arm was superior at the 90-day follow-up with 73.4% (47 of 64) responders compared with 36.5% (23 of 63) in the sham arm (p < 0.001). The primary endpoint analysis included 127 participants (64 active, 63 sham) with 90-day results. Twelve US investigational centers enrolled 133 participants. Responders were defined as participants with a 30% or greater reduction in rTNSS relative to baseline. The primary endpoint was the comparison between the treatment and sham arms for the percentage of responders at 90 days. Patient-reported outcome measures included the rTNSS, standardized Rhinoconjunctivitis Quality of Life Questionnaire, and Nasal Obstruction Symptom Evaluation (NOSE) questionnaires. Follow-up visits occurred at 30 and 90 days postprocedure. Participants were required to have minimum reflective Total Nasal Symptom Scores (rTNSSs) of 4 for total, 2 for rhinorrhea, and 1 for nasal congestion. Adults with moderate/severe symptoms of chronic rhinitis who were candidates for cryotherapy under local anesthesia were enrolled. One Rhino 7. The demo version of Rhinoceros can always be used as a viewer of Rhinoceros files and other supported file formats. After 90 days, saving and plug-ins stop working, unless you buy a license. The predetermined sample size was 61 participants per arm. Try the full version of Rhinoceros for free for 90 days Download your evaluation version here. This study was a prospective, multicenter, 1:1 randomized, sham-controlled, patient-blinded trial. The purpose of this study was to test whether cryotherapy is superior to a sham procedure for reducing symptoms of chronic rhinitis.
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